April 25, 2024

COVID-19 is linked to new diabetes cases—but long-term problems could be more severe – National Geographic UK

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Almost daily, microbiologist Peter Jackson receives emails from people who recovered from COVID-19 only to discover that their health troubles have just begun.

Recently, a mother of two in her 30s wrote to the Stanford University professor to say that she now takes a slew of diabetes med…….

Almost daily, microbiologist Peter Jackson receives emails from people who recovered from COVID-19 only to discover that their health troubles have just begun.

Recently, a mother of two in her 30s wrote to the Stanford University professor to say that she now takes a slew of diabetes medications every day—even though she hadn’t been at risk for the disease before her coronavirus infection.

Experts have known since the beginning of the pandemic that having diabetes—a condition when the body doesn’t make enough insulin or use it well enough to counteract a rise in blood sugar—is a risk factor for more severe COVID-19 infections. But they have also long suspected that the inverse might be true as well. In May, Jackson published a study in the journal Cell Metabolism showing that SARS-CoV-2 infects cells in the pancreas that produce insulin and may even target and destroy them—suggesting that the virus may also cause diabetes. (Why scientists began investigating the link between COVID-19 and diabetes.)

“This is a real thing,” Jackson says of the complaints from newly diabetic people that have flooded his inbox. Although some experts argue that the condition is rare, Jackson says the data suggests that in 2020 as many as 100,000 people were diagnosed with an unexpected case of diabetes.

He is one of many scientists who worry there could be a new wave of diabetes patients who will have to monitor their blood sugar levels for the rest of their lives. But he and his colleagues are also concerned that the virus may be harming the pancreas in ways that may not be visible now but could one day have troubling implications for the organ itself and for the rest of the digestive system.

“This could be a pandemic in a pandemic,” says Paolo Fiorina, a professor of endocrinology at the University of Milan and lecturer at Harvard Medical School, who has also spearheaded investigations into the connection between COVID-19 and diabetes.

Scientists are still hashing out how serious a threat COVID-19 poses to the pancreas in the long term—and whether those who do develop diabetes are really stuck with it forever. Although it will take large studies and potentially many years to answer those questions, researchers are already on the case.

How COVID damages the pancreas

First, a refresher on the pancreas—an organ that plays a key role in the digestive system. Located behind the stomach, the widest part of the pancreas is connected to the small intestine, close to where the stomach empties partially digested food. There, the pancreas secretes a variety of juices to the mix to further break it down.

Most of that food is broken down into sugar that is released into …….

Source: https://www.nationalgeographic.co.uk/science-and-technology/2021/10/covid-19-is-linked-to-new-diabetes-cases-but-long-term-problems-could-be-more-severe

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