January 27, 2023

Are Ozempic and Wegovy Safe? All About the Diabetes and Obesity Drugs – PEOPLE

The obesity drug Wegovy was approved by the FDA in 2021, and since then, it’s become a trending topic on social media and popular among celebrities for weight loss.

Some doctors have expressed frustration that Wegovy and its counterpart Ozempic, which is prescribed for diabetes, aren’t getting to people who need them, and the FDA has listed a …….

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The obesity drug Wegovy was approved by the FDA in 2021, and since then, it’s become a trending topic on social media and popular among celebrities for weight loss.


Some doctors have expressed frustration that Wegovy and its counterpart Ozempic, which is prescribed for diabetes, aren’t getting to people who need them, and the FDA has listed a shortage for both drugs.


The intended patient population for Wegovy is people with chronic obesity, and Ozempic is for those with type 2 diabetes. As many as 80% to 90% of individuals with type 2 diabetes struggle with obesity as well.


PEOPLE spoke with Ania Jastreboff, M.D., PhD., an obesity medicine physician scientist at Yale University, who is trained as both an adult endocrinologist and a pediatric endocrinologist, to better understand these drugs. Jastreboff spends the majority of her time studying these medications — how they work and who they work for — and then caring for patients with obesity.


Are Wegovy and Ozempic the same drug?


They are both semaglutide. Semaglutide is branded as Ozempic for the treatment of type 2 diabetes, and semaglutide is branded as Wegovy for the treatment of obesity. It is the same molecule that is used for both indications.


The semaglutide Ozempic for diabetes goes up to a dose of two milligrams weekly, and semaglutide Wegovy for weight loss goes up to a once-weekly dose of 2.4 milligrams.


So obesity is a disease?


Obesity is a neurometabolic disease. It is a chronic, treatable disease. We really need to treat obesity as we treat any other chronic disease, with effective and safe approaches that target underlying disease mechanisms.



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Source: https://news.google.com/__i/rss/rd/articles/CBMiKWh0dHBzOi8vcGVvcGxlLmNvbS9oZWFsdGgvaXMtd2Vnb3Z5LXNhZmUv0gEA?oc=5